Paediatric Liver Transplant

Understanding

What is Paediatric Liver Transplant?

Paediatric Liver Transplant is a highly specialized surgical procedure performed in infants, children, and adolescents suffering from severe liver disease, liver failure, metabolic disorders, or congenital liver conditions. The procedure involves replacing a diseased liver with a healthy donor liver, enabling the child to lead a healthier and more active life.

Our multidisciplinary paediatric transplant team provides comprehensive care, from diagnosis and evaluation to transplantation and long-term follow-up.

Causes of Liver Disease Requiring Paediatric Liver Transplant

  • Biliary Atresia

The most common reason for liver transplantation in children. The bile ducts are absent or blocked, causing progressive liver damage.

  • Acute Liver Failure

Sudden and severe loss of liver function due to infections, medications, toxins, or unknown causes.

  • Metabolic Liver Disorders

Inherited conditions that affect how the body processes nutrients and substances, including:

  1. Wilson’s Disease

  2. Tyrosinemia

  3. Glycogen Storage Disorders

  4. Alpha-1 Antitrypsin Deficiency

Types Of

Paediatric Liver Transplant

Paediatric Split Liver Transplant

What is a Paediatric Split Liver Transplant?

A Split Liver Transplant involves dividing a deceased donor liver into two portions. One portion is transplanted into a child while the remaining portion is used for another recipient, usually an adult.This approach helps maximize donor organ utilization while providing life-saving treatment to children awaiting transplantation.

Benefits

  • Increased availability of donor organs
  • Reduced waiting time
  • Excellent long-term outcomes
  • Effective use of deceased donor organs
  • Suitable for infants and young children

Paediatric Living Donor Liver Transplant

What is a Paediatric Living Donor Liver Transplant?

In this procedure, a healthy living donor—usually a parent or close relative—donates a portion of their liver to the child. Since the liver can regenerate, both donor and recipient livers grow back to near-normal size after surgery.

This is one of the most commonly performed paediatric liver transplant procedures.

Benefits

  • Timely transplantation
  • Reduced waiting-list mortality
  • Planned and scheduled surgery
  • Excellent graft survival rates
  • Better outcomes in critically ill children

Paediatric Monosegment Liver Pransplant

What is Paediatric Monosegment Liver Pransplant?

Monosegment Liver Transplant is an advanced transplant technique used primarily for very small infants and newborns. Only a single liver segment from a donor is transplanted, ensuring the graft size is appropriate for the child’s body.

This highly specialized procedure is performed in selected cases where conventional grafts may be too large.

Benefits

  • Ideal for small infants
  • Improved graft size matching
  • Reduced surgical complications
  • Better abdominal closure
  • Excellent outcomes in experienced centers

Must Know About Paediatric Liver Transplant

  • Conditions Requiring Paediatric Liver Transplant

    A liver transplant may be recommended for children with:

    • Biliary Atresia

    • Acute Liver Failure

    • Metabolic Liver Disorders

    • Wilson’s Disease

    • Progressive Familial Intrahepatic Cholestasis (PFIC)

    • Alagille Syndrome

    • Autoimmune Liver Disease

    • Liver Tumors

    • Chronic Liver Failure

    • Congenital Liver Disorders

  • Symptoms That May Indicate the Need for Transplant

    • Persistent jaundice

    • Poor growth and weight gain

    • Abdominal swelling

    • Recurrent infections

    • Severe itching

    • Easy bruising or bleeding

    • Feeding difficulties

    • Developmental delays

    • Liver failure complications

  • Benefits of Paediatric Liver Transplant

    • Restores normal liver function

    • Improves growth and development

    • Enhances quality of life

    • Improves nutrition and energy levels

    • Prevents complications of liver failure

    • Offers long-term survival and healthy childhood development

  • Diagnosis and Evaluation

    Comprehensive evaluation includes:

    • Paediatric hepatology assessment

    • Liver function tests

    • Blood group compatibility testing

    • Ultrasound and Doppler studies

    • CT Scan and MRI

    • Cardiac evaluation

    • Nutritional assessment

    • Infection screening

    • Donor evaluation when applicable

Frequently Asked Questions

Get answers to your questions

Q1: Who can be a living liver donor for a child?

A donor is usually:

  • A parent, sibling, or close relative
  • Between 18 and 55 years of age
  • In good physical and mental health
  • Blood group compatible with the child
  • Medically fit after comprehensive evaluation
Q2: Why is a living donor transplant preferred for children?

Living donor transplantation offers:

  • Reduced waiting time
  • Early treatment before complications worsen
  • Better surgical planning
  • Excellent success rates
  • Lower mortality while waiting for a donor organ
Q3: Can the liver grow back after donation?

Yes. The liver has a unique ability to regenerate. Both the donor’s remaining liver and the transplanted liver segment grow over time and regain normal function.

Q4: What is the success rate of Paediatric Living Donor Liver Transplant?

With modern surgical techniques and experienced transplant teams, paediatric living donor liver transplantation has excellent success rates and long-term outcomes.